Aspergers Children: Medication & Side Effects

Kids who have Aspergers (high functioning autism) think and function very differently than other kids. In most cases, they need special help and coaching to function more successfully in their school and home environments. Treatments for Aspergers focus on helping kids manage in these settings.

Special education services, behavior therapy, speech therapy, and physical or occupational therapy may help the youngster learn to function more effectively and harmoniously with others. Training and counseling for parents and other family members also may be helpful.

There are no specific medications used to treat Aspergers. However, kids who suffer from anxiety, depression, hyperactivity, or obsessive-compulsive disorder as a result of Aspergers may benefit from medication to help with these symptoms. When these medications are prescribed, the youngster will be monitored by his or her health care provider at regular intervals throughout treatment.

To treat depression, drugs such as fluoxetine (Prozac®, Sarafem®) may be prescribed. It is important for parents to work closely with the youngster's health care provider and to fully understand how to monitor the youngster for side effects of antidepressant medication. In some kids and teenagers, these medications may increase suicidal thoughts and actions.

Other side effects that should be reported to the youngster's health care provider immediately include the following:

• Aggressive or impulsive behavior
• Agitation or restlessness
• Increased activity level
• Increased chattiness
• Increased depression or anxiety
• Increased irritability
• Panic attacks
• Sleep difficulties
• Strange moods or behavior changes

Kids should be monitored especially closely when they first begin taking antidepressant medication or if the dosage of the medication is changed. These medications should not be discontinued or the dosage changed without consulting a qualified health care provider.

To treat obsessive-compulsive behavior (OCD), clomipramine (Anafranil®) may be prescribed. Clomipramine is also an antidepressant and increases the risk for suicidal thoughts and actions in kids and teens. Patients should be monitored closely while taking this medication. Side effects that should be reported immediately to the youngster's health care provider include the following:

• Weakness
• Tremors
• Tiredness
• Seizures
• Muscle stiffness
• Loss of bladder control or difficulty with urination
• Increased heart rate
• Hallucinations
• Eye pain
• Depression
• Breathing difficulties

The following side effects, which generally are less serious, should be reported to the youngster's health care provider if they persist or cause particular discomfort:

• Sinus congestion
• Nervousness
• Loss of memory or difficulty concentrating
• Intestinal symptoms
• Headache
• Drowsiness
• Changes in appetite

These medications should not be discontinued or the dosage changed without consulting a qualified health care provider.

To treat inattentiveness or hyperactivity, stimulants such as methylphenidate (Concerta®, Ritalin®) or dextroamphetamine (Dexadrine®) may be prescribed. These medications can be habit forming and should be used with caution in patients who have heart problems or psychiatric conditions. The youngster's health care provider will take a careful health history and perform a medical evaluation before prescribing this medication.

Methylphenidate and dextroamphetamine can interfere with the youngster's growth and weight gain. If this occurs, the youngster's health care provider should be contacted right away. The following serious side effects also should be reported immediately:

• Vision problems
• Speech difficulties
• Shortness of breath
• Seizures
• Pounding heartbeat
• Numbness in arms or legs
• Muscle weakness
• Mood changes
• Hives
• Hallucinations
• Extreme tiredness
• Dizziness
• Distorted perceptions of reality
• Chest pain

The following side effects generally are less serious and should be reported to the youngster's health care provider if they persist or cause particular discomfort:

• Sleep problems
• Shakiness, nervousness, or restlessness
• Nausea or vomiting
• Loss of appetite
• Headache
• Gastrointestinal distress
• Dry mouth

These medications should not be discontinued or the dosage changed without consulting a qualified health care provider.


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